Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.64 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500719 | 0.88 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL29463823 | 0.88 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| Potassium SCHEMBL10510827 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10511115 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10511131 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10510815 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL584841 | 0.86 | TOP2A (0.68) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL30320686 | 0.86 | TOP2A (0.68) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8322131 | 0.85 | TOP2A (0.47) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8138660 | 0.85 | TOP2A (0.47) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5679689-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0184035-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0216245-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0183129-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| US-4826982-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0216245-A1 | Quinolonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |
| EP-0207497-A2 | Quinolonecarboxylic acid derivative and process for its preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
| EP-0184035-A1 | Quinolonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-06-11 | — | — | EP | disclosed |
| EP-0183129-A1 | Quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |