SCHEMBL30320686

SCHEMBL30320686

O=C(O)c1cn(C2CC2)c2c(O)c(F)c(F)cc2c1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 7/20 0.68
TOP2B Q02880 7/20 0.68
ALDH1A1 P00352 5/20 0.55
POLB P06746 2/20 0.55
OPRM1 P35372 2/20 0.55
CHRM2 P08172 1/20 0.55
CHRM1 P11229 1/20 0.55
OPRD1 P41143 1/20 0.55
KCNH2 Q12809 5/20 0.53
KDM4E B2RXH2 4/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
LMNA P02545 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
PRKD3 O94806 1/20 0.51
ALOX15 P16050 1/20 0.51
CLK2 P49760 1/20 0.51
CLK4 Q9HAZ1 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584841 1.00 TOP2A (0.68) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL500719 0.90 TOP2A (0.71) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL29463823 0.90 TOP2A (0.71) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL14209463 0.89 TOP2A (0.55) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL10511131 0.88 TOP2A (0.69) TOP2ATOP2BALDH1A1POLBOPRM1
Potassium SCHEMBL10510827 0.88 TOP2A (0.69) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL10511115 0.88 TOP2A (0.69) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL10510815 0.88 TOP2A (0.69) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL500386 0.86 ALDH1A1 (0.66) TOP2ATOP2BALDH1A1POLBOPRM1
SCHEMBL8324772 0.86 TOP2A (0.64) TOP2ATOP2BALDH1A1POLBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115785095-B Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2024-07-09 CN claimed
WO-2023218472-A1 AN AQUEOUS OPHTHALMIC SOLUTION OF NSAIDS AND FLUOROQUINOLONE ANTIBIOTIC AND PROCESS OF PREPARATION THEREOF AKUMS DRUGS & PHARMACEUTICALS LIMITED (IN) 2023-11-16 WO claimed
CN-218871961-U Preparation facilities of moxifloxacin impurity 江苏信和生物医药有限公司 2023-04-18 CN claimed
CN-115785095-A Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2023-03-14 CN claimed
CN-119936246-A Method for detecting N-nitrosomoxifloxacin in moxifloxacin hydrochloride sodium chloride injection 安徽博诺美科生物医药有限公司 2025-05-06 CN disclosed
CN-118937545-B Separation detection method for moxifloxacin and impurities thereof 成都普什制药有限公司 2025-01-28 CN disclosed
CN-118937545-A Separation detection method for moxifloxacin and impurities thereof 成都普什制药有限公司 2024-11-12 CN disclosed
CN-115785095-B Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2024-07-09 CN disclosed
CN-115785095-B Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2024-07-09 CN disclosed
CN-115785095-B Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2024-07-09 CN disclosed
CN-118047721-A Quinoline carboxylic acid derivative and application thereof 沈阳中化农药化工研发有限公司 2024-05-17 CN disclosed
WO-2023218472-A1 AN AQUEOUS OPHTHALMIC SOLUTION OF NSAIDS AND FLUOROQUINOLONE ANTIBIOTIC AND PROCESS OF PREPARATION THEREOF AKUMS DRUGS & PHARMACEUTICALS LIMITED (IN) 2023-11-16 WO disclosed
CN-113092644-B Method for simultaneously detecting content of moxifloxacin and intermediate thereof 江苏八巨药业有限公司 2023-05-09 CN disclosed
CN-218871961-U Preparation facilities of moxifloxacin impurity 江苏信和生物医药有限公司 2023-04-18 CN disclosed
CN-218871961-U Preparation facilities of moxifloxacin impurity 江苏信和生物医药有限公司 2023-04-18 CN disclosed
CN-218871961-U Preparation facilities of moxifloxacin impurity 江苏信和生物医药有限公司 2023-04-18 CN disclosed
CN-115785095-A Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2023-03-14 CN disclosed
CN-115785095-A Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2023-03-14 CN disclosed
CN-115785095-A Preparation and purification method of moxifloxacin impurity RC-4 上海熙华药业有限公司 2023-03-14 CN disclosed