SCHEMBL8324976

SCHEMBL8324976

CCc1c(C(F)(F)F)n[nH]c1O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.33
P2RX7 Q99572 2/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8802950 0.78 P2RX7 (0.39) KDM5BP2RX7KDM4EPOLBMAPT
SCHEMBL18373780 0.76 KDM5B (0.33) KDM5B
SCHEMBL25001945 0.76 KDM5B (0.33) KDM5BP2RX7
SCHEMBL6853189 0.74 HCAR2 (0.38) KDM5BP2RX7KDM4EPOLBMAPT
SCHEMBL20471491 0.73 HCAR2 (0.36)
SCHEMBL8803104 0.73 KDM5B (0.35) KDM5B
SCHEMBL8185143 0.72 NR2F2 (0.32)
SCHEMBL4278367 0.72
SCHEMBL22303620 0.71 KDM4C (0.42) KDM5BP2RX7KDM4EPOLBMAPT
SCHEMBL13683162 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789698-B1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOW AGROSCIENCES LLC (US) 1999-07-07 EP disclosed
EP-0789698-A1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOWELANCO (US) 1997-08-20 EP disclosed
WO-1997008172-A1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOWELANCO (US) 1997-03-06 WO disclosed