SCHEMBL8325012

SCHEMBL8325012

COCCCCCC(=O)CP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
TSHR P16473 2/20 0.37
LPAR3 Q9UBY5 3/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR2 Q9HBW0 2/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
BLM P54132 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 2/20 0.32
DGKA P23743 1/20 0.31
ENO1 P06733 1/20 0.31
ENPP2 Q13822 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7947621 0.92 ALDH1A1 (0.43) ALDH1A1TSHRKMT2AMEN1LMNA
SCHEMBL30432418 0.83 ALDH1A1 (0.70) ALDH1A1TSHRKMT2ALMNAMAPT
SCHEMBL24800393 0.83 ALDH1A1 (0.70) ALDH1A1TSHRKMT2ALMNAMAPT
SCHEMBL7951205 0.82 ALDH1A1 (0.53) ALDH1A1TSHRLPAR3LPAR1LPAR2
SCHEMBL11849529 0.80 TSHR (0.54) ALDH1A1TSHRKMT2AMEN1LMNA
SCHEMBL8582114 0.80 ALDH1A1 (0.50) ALDH1A1TSHRLPAR3LPAR2KMT2A
SCHEMBL7741804 0.79 KMT2A (0.54) ALDH1A1TSHRLPAR3LPAR2KMT2A
SCHEMBL8583505 0.79 KMT2A (0.54) ALDH1A1TSHRLPAR3LPAR2KMT2A
SCHEMBL8414887 0.79 KMT2A (0.54) ALDH1A1TSHRLPAR3LPAR2KMT2A
SCHEMBL10709425 0.79 KMT2A (0.54) ALDH1A1TSHRLPAR3LPAR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886034-A ANTIULCER AGENTS KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) 1999-03-23 US disclosed
US-5534547-A Prostaglandins of the D series, and tranquilizers and soporifics containing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1996-07-09 US disclosed
US-5284858-A Prostaglandins E and anti ulcers containing same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1994-02-08 US disclosed
US-5225439-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1993-07-06 US disclosed
US-5166174-A For duodenal ulcers or gastric ulcers K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-11-24 US disclosed
EP-0284180-B1 PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-08-19 EP disclosed
US-5137915-A PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-08-11 US disclosed
US-5106869-A Vasopressor activity without ephemeral vasorelaxation; no effect on trachea, intestine K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-04-21 US disclosed
EP-0281239-B1 PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-03-25 EP disclosed
US-5073569-A 13,14-dihydro-15-keto- K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1991-12-17 US disclosed
EP-0284180-A1 Prostaglandins E and anti ulcers containing same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-28 EP disclosed
EP-0281239-A2 Prostaglandins of the D series, and tranquilizers and soporifics containing the same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-07 EP disclosed