Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318786 | 0.88 | KMT2A (0.46) | LRRK2GBA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2952409 | 0.77 | ALDH1A1 (0.46) | GBA1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL27032805 | 0.76 | FOLH1 (0.48) | MEN1KMT2ASMN1; SMN2PTGER1FOLH1 | |
| SCHEMBL15058040 | 0.75 | MAPT (0.49) | SMN1; SMN2NPC1RAB9APTGER1HTT | |
| SCHEMBL30369233 | 0.75 | MAPT (0.49) | SMN1; SMN2NPC1RAB9APTGER1HTT | |
| SCHEMBL601741 | 0.75 | FOLH1 (0.50) | MEN1KMT2APTGER1FOLH1KDM4E | |
| SCHEMBL5583791 | 0.73 | RXRA (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1263372 | 0.72 | HRH4 (0.49) | SMN1; SMN2NPC1RAB9AHRH3HTT | |
| SCHEMBL30440467 | 0.72 | HRH4 (0.49) | SMN1; SMN2NPC1RAB9AHRH3HTT | |
| SCHEMBL1318540 | 0.72 | LRRK2 (0.64) | LRRK2MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567133-B1 | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5403816-A | Picolinic acid derivative and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-04 | — | — | US | disclosed |
| EP-0567133-A1 | Picolinic acid derivative and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |