Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | PTGIR | P43119 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692233 | 0.87 | MEN1 (0.61) | MEN1KMT2APOLBKDM4EHRH2 | |
| SCHEMBL14198699 | 0.86 | MAPT (0.67) | MEN1KMT2APOLBKDM4EHRH2 | |
| SCHEMBL3705572 | 0.85 | MEN1 (0.59) | MEN1KMT2APOLBKDM4EHRH2 | |
| SCHEMBL3696610 | 0.83 | MEN1 (0.57) | MEN1KMT2APOLBKDM4EHRH2 | |
| SCHEMBL8326524 | 0.83 | ALDH1A1 (0.59) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL4854395 | 0.82 | GAA (0.59) | MEN1KMT2AKDM4ESIGMAR1 | |
| SCHEMBL8326661 | 0.82 | KMT2A (0.57) | MEN1KMT2APOLBKDM4E | |
| SCHEMBL8232974 | 0.81 | HRH4 (0.60) | KMT2AKDM4EHRH2PTGIRSIGMAR1 | |
| SCHEMBL8325440 | 0.81 | MAOB (0.51) | MEN1KMT2APOLB | |
| SCHEMBL992110 | 0.81 | CYP2D6 (0.62) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |