Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854395 | 0.86 | GAA (0.59) | MAOBCYP2D6MEN1KMT2AMAOA | |
| SCHEMBL6311179 | 0.85 | MAOB (0.55) | MAOBMEN1KMT2AMAOA | |
| SCHEMBL17916771 | 0.85 | POLB (0.54) | MAOBCYP2D6POLBMEN1KMT2A | |
| SCHEMBL992110 | 0.84 | CYP2D6 (0.62) | MAOBCYP2D6BCHEACHEALDH1A1 | |
| SCHEMBL3782330 | 0.84 | ALDH1A1 (0.59) | CYP2D6POLBBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL31687488 | 0.83 | CYP2D6 (0.60) | MAOBCYP2D6BCHEACHEALDH1A1 | |
| SCHEMBL18105383 | 0.83 | ALDH1A1 (0.60) | MAOBPOLBMEN1KMT2AMAOA | |
| SCHEMBL8328716 | 0.82 | CYP1A2 (0.49) | CYP2D6POLBMEN1KMT2AGAA | |
| SCHEMBL8325191 | 0.81 | MEN1 (0.57) | POLBMEN1KMT2A | |
| SCHEMBL8329828 | 0.81 | POLB (0.59) | CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |