Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 13/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705954 | 0.95 | ESR1 (0.47) | ALDH1A1LTA4HGAAESR1ESR2 | |
| SCHEMBL13412705 | 0.92 | NR5A1 (0.51) | ALDH1A1LTA4HGAAESR1ESR2 | |
| SCHEMBL8705661 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LTA4HGAAESR1ESR2 | |
| SCHEMBL9573808 | 0.87 | GAA (0.44) | ALDH1A1LTA4HGAAESR1ESR2 | |
| SCHEMBL9573819 | 0.84 | GAA (0.45) | ALDH1A1GAAESR1ESR2GLA | |
| SCHEMBL8705625 | 0.83 | ALDH1A1 (0.63) | ALDH1A1GAAESR1ESR2MAPT | |
| SCHEMBL8802445 | 0.81 | GAA (0.54) | ALDH1A1GAAESR1ESR2MAPT | |
| SCHEMBL9726098 | 0.81 | GAA (0.47) | ALDH1A1GAAESR1ESR2MAPT | |
| SCHEMBL8809032 | 0.81 | GAA (0.49) | ALDH1A1GAAESR1ESR2MAPT | |
| SCHEMBL8707515 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605404-B1 | Polycyclic dyes | BASF AG (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0559345-B1 | Polycyclic dyes | BASF AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5717112-A | Benzofuranone and benzodifuranone compounds | ZENECA LIMITED (GB) | 1998-02-10 | — | — | US | disclosed |
| EP-0575056-B1 | Preparation of polycyclic dyes | BASF AG (DE) | 1997-09-17 | — | — | EP | disclosed |
| US-5663371-A | Process for preparing polycyclic dyes | ZENECA LIMITED (GB) | 1997-09-02 | — | — | US | disclosed |
| EP-0669922-B1 | BENZOFURANONES, BENZODIFURANTRIONES AND PROCESSES FOR THE PREPARATION OF BENZODIFURANDIONES | BASF AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| US-5625080-A | Benzodifurantrione compounds and process | ZENECA LIMITED (GB) | 1997-04-29 | — | — | US | disclosed |
| EP-0502278-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1997-03-05 | — | — | EP | disclosed |
| EP-0673400-A1 | POLYCYCLIC DYES | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0669922-A1 | BENZOFURANONE AND BENZODIFURANTRIONE DERIVATIVES AND PROCESS FOR THE PREPARATION OF BENZODIFURANONES. | ZENECA LTD (GB) | 1995-09-06 | — | — | EP | disclosed |
| US-5189181-A | Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| EP-0502278-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1992-09-09 | — | — | EP | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0182507-B1 | HETERO-POLYCYCLIC DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE IN COLOURATION OF TEXTILE MATERIALS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |
| US-4916240-A | Hetero-polycyclic aromatic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-10 | — | — | US | disclosed |
| EP-0294029-A2 | Hetero-polycyclic aromatic compounds | ZENECA LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4680417-A | 2.6-dioxo-2.6-dehydrobenzo[1:2-b,4:5-b]difurans | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-14 | — | — | US | disclosed |
| EP-0182507-A2 | Hetero-polycyclic dyestuffs, methods for their preparation and their use in colouration of textile materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-28 | — | — | EP | disclosed |