Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 13/20 | 0.77 |
| ▸ | MMP13 | P45452 | 10/20 | 0.77 |
| ▸ | MMP2 | P08253 | 1/20 | 0.77 |
| ▸ | MMP9 | P14780 | 1/20 | 0.77 |
| ▸ | MMP14 | P50281 | 1/20 | 0.77 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613354 | 0.87 | MMP12 (1.00) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL8325840 | 0.86 | MMP12 (0.74) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613401 | 0.85 | MMP12 (0.79) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613464 | 0.84 | MMP12 (0.77) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613537 | 0.84 | MMP12 (0.77) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5660776 | 0.84 | MMP12 (0.77) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613397 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613430 | 0.80 | MMP12 (0.72) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613483 | 0.80 | MMP12 (1.00) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5613380 | 0.80 | MMP12 (1.00) | MMP12MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110974-A1 | MATRIX METALLOPROTEINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |