Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923870 | 0.95 | KCNH2 (0.42) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL8325561 | 0.88 | KCNH2 (0.34) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL8923882 | 0.87 | KCNH2 (0.35) | KCNH2HRH3ALDH1A1TOP2ATOP2B | |
| SCHEMBL8323756 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8323773 | 0.78 | MEN1 (0.60) | KCNH2HRH3ALDH1A1KDM4EHPGD | |
| SCHEMBL8922496 | 0.77 | MEN1 (0.58) | KCNH2HRH3ALDH1A1TOP2ATOP2B | |
| SCHEMBL8322412 | 0.77 | CACNA1F (0.62) | KCNH2TOP2ATOP2BMEN1KMT2A | |
| SCHEMBL8322078 | 0.76 | MEN1 (0.51) | KCNH2HRH3ALDH1A1TOP2ATOP2B | |
| SCHEMBL8322523 | 0.76 | KMT2A (0.40) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8324813 | 0.75 | KCNH2 (0.53) | KCNH2ALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |