Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923870 | 0.93 | KCNH2 (0.42) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL8325558 | 0.87 | KCNH2 (0.46) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL8325561 | 0.82 | KCNH2 (0.34) | KCNH2HRH3ALDH1A1TOP2ATOP2B | |
| SCHEMBL8923856 | 0.78 | KMT2A (0.33) | POLBKMT2AALDH1A1 | |
| SCHEMBL8923183 | 0.75 | KCNH2 (0.43) | KCNH2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8922496 | 0.73 | MEN1 (0.58) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL8926299 | 0.73 | ALDH1A1 (0.52) | KCNH2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8323773 | 0.71 | MEN1 (0.60) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL8323756 | 0.71 | KDM4E (0.58) | ALDH1A1TOP2ATOP2B | |
| SCHEMBL8923852 | 0.70 | KMT2A (0.39) | POLBMEN1KMT2AALDH1A1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679689-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |