Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325558 | 0.88 | KCNH2 (0.46) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL8923870 | 0.84 | KCNH2 (0.42) | KCNH2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL8323758 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8923882 | 0.82 | KCNH2 (0.35) | KCNH2HRH3ALDH1A1TOP2ATOP2B | |
| SCHEMBL8323776 | 0.79 | MEN1 (0.44) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8322415 | 0.78 | KCNH2 (0.47) | KCNH2TOP2ATOP2B | |
| SCHEMBL8322083 | 0.77 | MEN1 (0.37) | KCNH2TOP2ATOP2B | |
| SCHEMBL8322527 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8324816 | 0.76 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8322831 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |