Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319499 | 0.72 | HTR4 (0.61) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| Hydrochloric Acid SCHEMBL7400556 | 0.71 | HTR4 (0.60) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL6944812 | 0.63 | KCNH2 (0.55) | KCNH2 | |
| Bromide SCHEMBL5227181 | 0.60 | GNAI3 (0.44) | HTR4ADRA2CHTR1DHTR2BADRA1B | |
| Tert-Butylamine SCHEMBL28089805 | 0.60 | KCNH2 (0.49) | LMNAKCNH2 | |
| SCHEMBL8397190 | 0.60 | KCNH2 (0.43) | HTR4PMP22NPSR1CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL8394495 | 0.59 | GNAI3 (0.42) | HTR4CHRM3KCNH2 | |
| SCHEMBL396677 | 0.59 | KCNH2 (0.61) | KCNH2 | |
| Acetic Acid SCHEMBL4538190 | 0.59 | POLB (0.49) | ADRA1AADRA2ADRD3SIGMAR1KCNH2 | |
| SCHEMBL5227695 | 0.59 | SMN1; SMN2 (0.67) | LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604494-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-28 | — | — | EP | claimed |