Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964482 | 0.98 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8325842 | 0.97 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7984203 | 0.89 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8358690 | 0.83 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7416384 | 0.81 | MAPT (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8326260 | 0.80 | PDE4D (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7987695 | 0.80 | MAPT (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7970614 | 0.80 | NAMPT (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7980464 | 0.79 | PDE7A (0.52) | — | |
| SCHEMBL7379307 | 0.79 | TEAD1 (0.53) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047817-A1 | PDE4 AND PDE3/4 INHIBITORS FOR USE IN THE TREATMENT OF CACHEXIA | ALTANA PHARMA AG (DE) | 2004-06-10 | — | — | WO | disclosed |