Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.69 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328479 | 0.97 | ACAT1 (0.69) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6635566 | 0.94 | ACAT1 (0.75) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8328255 | 0.93 | ACAT1 (0.68) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8325491 | 0.93 | ACAT1 (0.64) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8329049 | 0.92 | ACAT1 (0.74) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8326825 | 0.92 | ACAT1 (0.63) | ACAT1SOAT1 | |
| SCHEMBL6636574 | 0.91 | ACAT1 (0.75) | ACAT1SOAT1PDE4A | |
| SCHEMBL8329227 | 0.91 | ACAT1 (0.57) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8327151 | 0.90 | ACAT1 (0.66) | ACAT1SOAT1 | |
| SCHEMBL8326341 | 0.89 | ACAT1 (0.74) | ACAT1SOAT1PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |