Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329642 | 0.95 | ACAT1 (0.56) | ACAT1SOAT1 | |
| SCHEMBL8330915 | 0.94 | ACAT1 (0.55) | ACAT1SOAT1 | |
| SCHEMBL8327366 | 0.91 | ACAT1 (0.56) | ACAT1SOAT1 | |
| SCHEMBL8324340 | 0.91 | ACAT1 (0.61) | ACAT1SOAT1HTR3EHTR3BHTR3A | |
| SCHEMBL8331699 | 0.90 | ACAT1 (0.57) | ACAT1SOAT1 | |
| SCHEMBL8326879 | 0.89 | ACAT1 (0.58) | ACAT1SOAT1 | |
| SCHEMBL8468376 | 0.89 | ACAT1 (0.60) | ACAT1SOAT1HTR3EHTR3BHTR3A | |
| SCHEMBL8328523 | 0.89 | ACAT1 (0.60) | ACAT1SOAT1HTR3EHTR3BHTR3A | |
| SCHEMBL8323123 | 0.89 | ACAT1 (0.60) | ACAT1SOAT1HTR3EHTR3BHTR3A | |
| SCHEMBL8328195 | 0.89 | ACAT1 (0.56) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |