Sugi Predict

Sugi Predict / Compounds / SCHEMBL8329642

SCHEMBL8329642

SCHEMBL8329642

CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(C#CCN(C)Cc3ccccc3)c2)c2cccnc21

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ACAT1 P24752 1/20 0.56
▸ SOAT1 P35610 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8326410 0.95 ACAT1 (0.56) ACAT1SOAT1
SCHEMBL8330915 0.94 ACAT1 (0.55) ACAT1SOAT1
SCHEMBL8331699 0.94 ACAT1 (0.57) ACAT1SOAT1
SCHEMBL8328195 0.93 ACAT1 (0.56) ACAT1SOAT1
SCHEMBL8327366 0.93 ACAT1 (0.56) ACAT1SOAT1
SCHEMBL8324340 0.91 ACAT1 (0.61) ACAT1SOAT1
SCHEMBL8468376 0.89 ACAT1 (0.60) ACAT1SOAT1
SCHEMBL8328523 0.89 ACAT1 (0.60) ACAT1SOAT1
SCHEMBL8323123 0.89 ACAT1 (0.60) ACAT1SOAT1
SCHEMBL8325685 0.89 ACAT1 (0.53) ACAT1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0947515-A1 NOVEL NAPHTHYRIDINE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-10-06 — — EP disclosed