Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324319 | 0.88 | HDAC1 (0.62) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL8322714 | 0.81 | ALDH1A1 (0.61) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL10475479 | 0.80 | GAA (0.66) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL8320365 | 0.79 | HDAC1 (0.78) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL8324002 | 0.77 | HDAC1 (0.59) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL28357772 | 0.77 | KDM4E (0.63) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL28357770 | 0.77 | KDM4E (0.63) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Bendazol SCHEMBL309393 | 0.77 | GAA (1.00) | GAAPKMSMN1; SMN2ALDH1A1HPGD | |
| Bendazol SCHEMBL29539948 | 0.77 | GAA (1.00) | GAAPKMSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23603266 | 0.76 | GAA (0.69) | HDAC1HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |