Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | STK4 | Q13043 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325264 | 0.92 | PDE4B (0.51) | CSF1RSMN1; SMN2GAAPDE4BNPSR1 | |
| SCHEMBL8327280 | 0.92 | PDE4B (0.51) | CSF1RSMN1; SMN2GAAPDE4BNPSR1 | |
| SCHEMBL8565165 | 0.85 | PDE4B (0.52) | SMN1; SMN2GAAPDE4BNPSR1MAPT | |
| SCHEMBL8565169 | 0.85 | PDE4B (0.52) | SMN1; SMN2GAAPDE4BNPSR1MAPT | |
| SCHEMBL8325273 | 0.85 | CSF1R (0.39) | CSF1RSMN1; SMN2GAAPDE4BSTK4 | |
| Hydrochloric Acid SCHEMBL8327789 | 0.85 | PDE4B (0.51) | SMN1; SMN2GAAPDE4BNPSR1MAPT | |
| SCHEMBL8564146 | 0.84 | CSF1R (0.50) | CSF1RSMN1; SMN2GAAPDE4BEGFR | |
| SCHEMBL8565303 | 0.79 | CSF1R (0.62) | CSF1RPDE4BEGFRERBB2 | |
| SCHEMBL8330039 | 0.77 | MAPT (0.44) | CSF1RSMN1; SMN2EGFRERBB2MAPT | |
| SCHEMBL8561203 | 0.77 | GAA (0.49) | CSF1RSMN1; SMN2GAAPDE4BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |