Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561277 | 0.90 | PDE4B (0.61) | GAASMN1; SMN2PDE4BMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL8563873 | 0.89 | PDE4B (0.60) | GAASMN1; SMN2PDE4BMAPTNPSR1 | |
| SCHEMBL8326516 | 0.88 | MEN1 (0.46) | GAASMN1; SMN2MAPTALDH1A1PAX8 | |
| SCHEMBL8330781 | 0.85 | GAA (0.47) | GAASMN1; SMN2PDE4BMAPTCSF1R | |
| SCHEMBL8329323 | 0.83 | GAA (0.47) | GAASMN1; SMN2PDE4BMAPTCSF1R | |
| SCHEMBL8564146 | 0.82 | CSF1R (0.50) | GAASMN1; SMN2PDE4BMAPTCSF1R | |
| SCHEMBL8566689 | 0.82 | PDE4B (0.43) | GAASMN1; SMN2PDE4BMAPTCSF1R | |
| SCHEMBL8565887 | 0.77 | GAA (0.50) | GAASMN1; SMN2PDE4BCSF1RNPSR1 | |
| SCHEMBL8329045 | 0.77 | MAPT (0.53) | GAASMN1; SMN2PDE4BMAPTNPSR1 | |
| SCHEMBL8326664 | 0.77 | CSF1R (0.48) | GAASMN1; SMN2PDE4BMAPTCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | claimed |