Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326664 | 0.85 | CSF1R (0.48) | CSF1RSTK4NPC1RAB9AMAPT | |
| SCHEMBL8327280 | 0.80 | PDE4B (0.51) | CSF1RMAPTALDH1A1PDE4BHTT | |
| SCHEMBL8325264 | 0.80 | PDE4B (0.51) | CSF1RMAPTALDH1A1PDE4BHTT | |
| SCHEMBL8328091 | 0.78 | SYK (0.38) | CSF1RNPC1CDK2MAPTALDH1A1 | |
| SCHEMBL8565165 | 0.74 | PDE4B (0.52) | MAPTALDH1A1PDE4BHTTNPSR1 | |
| SCHEMBL8565169 | 0.74 | PDE4B (0.52) | MAPTALDH1A1PDE4BHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL8327789 | 0.73 | PDE4B (0.51) | MAPTALDH1A1PDE4BHTTNPSR1 | |
| SCHEMBL8559298 | 0.73 | PDGFRA (0.48) | STK4NPC1RAB9AMAPTPDE4B | |
| SCHEMBL8559305 | 0.73 | PDGFRA (0.48) | STK4NPC1RAB9AMAPTPDE4B | |
| SCHEMBL8328465 | 0.72 | PTGS2 (0.40) | MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |