Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316240 | 0.95 | TSHR (0.40) | TSHRHPGDZDHHC20ZDHHC2HCAR2 | |
| SCHEMBL7889412 | 0.90 | TSHR (0.53) | TSHRHPGDZDHHC20ZDHHC2HCAR2 | |
| Methoxymethane SCHEMBL6651651 | 0.87 | TSHR (0.50) | TSHRHPGDZDHHC20ZDHHC2HCAR2 | |
| SCHEMBL7889404 | 0.85 | TSHR (0.49) | TSHRHPGDZDHHC20ZDHHC2HCAR2 | |
| SCHEMBL7897232 | 0.85 | TSHR (0.47) | TSHRHPGDZDHHC20ZDHHC2ACACB | |
| SCHEMBL9257784 | 0.85 | TSHR (0.40) | TSHRHPGDZDHHC20ZDHHC2ACACB | |
| Ether SCHEMBL9640045 | 0.84 | TSHR (0.47) | TSHRHPGDZDHHC20ZDHHC2HCAR2 | |
| SCHEMBL11121188 | 0.83 | TSHR (0.46) | TSHRACACBALDH1A1MAPK1TDP1 | |
| Methoxymethane SCHEMBL9257609 | 0.82 | TSHR (0.44) | TSHRHPGDZDHHC20ZDHHC2ACACB | |
| SCHEMBL26478883 | 0.82 | TSHR (0.48) | TSHRHPGDZDHHC20ZDHHC2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981648-A | CURABLE LATEX COMPOSITION COMPRISING AN EMULSION IN AN AQUEOUS MEDIUM; DOES NOT LIBERATE FORMALDEHYDE ON CURING; COATINGS | AL CHEM & CY US ACQUICO, INC. | 1999-11-09 | — | — | US | disclosed |
| EP-0224736-B1 | Curable compositions | AMERICAN CYANAMID CO (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0224736-A2 | Curable compositions | AMERICAN CYANAMID COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |
| US-4443623-A | Preparation of predominately methyl acrylamidoglycolate methyl ether in a normally liquid product | AMERICAN CYANAMID COMPANY (US) | 1984-04-17 | — | — | US | disclosed |