SCHEMBL7897232

SCHEMBL7897232

C=CC(=O)NC(O)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ACACB O00763 2/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
ALDH1A1 P00352 4/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
CAD P27708 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
METAP2 P50579 2/20 0.34
METAP1 P53582 1/20 0.34
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL9257609 0.96 TSHR (0.44) TSHRACACBMGAMGAASI
Ether SCHEMBL9252409 0.95 TSHR (0.42) TSHRACACBMGAMGAASI
SCHEMBL8326863 0.85 TSHR (0.44) TSHRACACBALDH1A1MAPK1TDP1
Ether SCHEMBL9262685 0.84 TSHR (0.42) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL11038902 0.83 TSHR (0.50) TSHRACACBGAAALDH1A1MAPK1
SCHEMBL10082440 0.82 TSHR (0.48) TSHRACACBMGAMGAASI
SCHEMBL7889412 0.82 TSHR (0.53) TSHRACACBALDH1A1ZDHHC20ZDHHC2
SCHEMBL3683866 0.82 TSHR (0.52) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9316240 0.81 TSHR (0.40) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL1794180 0.81 MAPT (0.44) TSHRACACBALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6171386-B1 HYDRAULIC CEMENTS AND WATER WITH POLYMER LATEX AN INTERPOLYMER LATEX IN AN AMOUNT FROM ABOUT 10% TO 50% BY WEIGHT OF CEMENT, THE INTERPOLYMER LATEX, COMPRISING DIENE, VINYL AROMATIC MONOMERS AND METH(ACRYLIC ACID MONOMERS BENCHMARK RESEARCH& TECHNOLOGY INC. 2001-01-09 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US claimed
EP-0470689-A1 Copolymer binders GENCORP INC. (US) 1992-02-12 EP claimed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-6171386-B1 HYDRAULIC CEMENTS AND WATER WITH POLYMER LATEX AN INTERPOLYMER LATEX IN AN AMOUNT FROM ABOUT 10% TO 50% BY WEIGHT OF CEMENT, THE INTERPOLYMER LATEX, COMPRISING DIENE, VINYL AROMATIC MONOMERS AND METH(ACRYLIC ACID MONOMERS BENCHMARK RESEARCH& TECHNOLOGY INC. 2001-01-09 US disclosed
US-5981648-A CURABLE LATEX COMPOSITION COMPRISING AN EMULSION IN AN AQUEOUS MEDIUM; DOES NOT LIBERATE FORMALDEHYDE ON CURING; COATINGS AL CHEM & CY US ACQUICO, INC. 1999-11-09 US disclosed
US-5629047-A IMPROVED TENSILE STRENGTH, LOW TEMPERATURE POLYMERIZATION GENCORP INC. (US) 1997-05-13 US disclosed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US disclosed
US-5369204-A Low molecular weight acrylamidoglycolate crosslinker and process CYTEC TECHNOLOGY CORP. (US) 1994-11-29 US disclosed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP disclosed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US disclosed
EP-0470689-A1 Copolymer binders GENCORP INC. (US) 1992-02-12 EP disclosed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP disclosed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US disclosed
US-4760168-A Preparation of alkyl acrylamidoglycolates and their alkyl ethers AMERICAN CYANAMID COMPANY (US) 1988-07-26 US disclosed
EP-0224736-A2 Curable compositions AMERICAN CYANAMID COMPANY (US) 1987-06-10 EP disclosed