Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326863 | 0.95 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9257784 | 0.90 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7889404 | 0.88 | TSHR (0.49) | TSHRHPGDALDH1A1HSD17B10ZDHHC20 | |
| SCHEMBL7889412 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1ZDHHC20ZDHHC2 | |
| Ether SCHEMBL9640045 | 0.83 | TSHR (0.47) | TSHRHPGDALDH1A1HSD17B10ZDHHC20 | |
| Methoxymethane SCHEMBL6651651 | 0.83 | TSHR (0.50) | TSHRHPGDALDH1A1HSD17B10ZDHHC20 | |
| SCHEMBL9000275 | 0.81 | TSHR (0.45) | TSHRHPGDALDH1A1HSD17B10ZDHHC20 | |
| SCHEMBL7897232 | 0.81 | TSHR (0.47) | TSHRHPGDALDH1A1HSD17B10ZDHHC20 | |
| Ether SCHEMBL9252409 | 0.80 | TSHR (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2ACACB | |
| SCHEMBL11121188 | 0.79 | TSHR (0.46) | TSHRALDH1A1HSD17B10ACACBTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369204-A | Low molecular weight acrylamidoglycolate crosslinker and process | CYTEC TECHNOLOGY CORP. (US) | 1994-11-29 | — | — | US | disclosed |
| US-4443623-A | Preparation of predominately methyl acrylamidoglycolate methyl ether in a normally liquid product | AMERICAN CYANAMID COMPANY (US) | 1984-04-17 | — | — | US | disclosed |