SCHEMBL832729

SCHEMBL832729

CCc1cc(Oc2cc(CC)c(N)c(CC)c2)cc(CC)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 3/20 0.36
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
P2RX3 P56373 1/20 0.34
P2RX2 Q9UBL9 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
ST14 Q9Y5Y6 1/20 0.33
NR4A1 P22736 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CYP3A4 P08684 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682268 0.84 ST14 (0.46) HTTPOLBALDH1A1SMN1; SMN2MAPT
SCHEMBL10522397 0.83 POLB (0.47) HTTPOLBALDH1A1MAPTMEN1
SCHEMBL5982078 0.82 P2RX3 (0.36) HTTPOLBALDH1A1MAPTMEN1
SCHEMBL28919511 0.81 TSHR (0.46) HTTPOLBALDH1A1SMN1; SMN2MAPT
SCHEMBL29201192 0.81 HTT (0.45) HTTPOLBALDH1A1MAPTNOS3
SCHEMBL3940715 0.81 HMGCR (0.35) HTTPOLBALDH1A1SMN1; SMN2NOS3
SCHEMBL3939086 0.78 TLR8 (0.39) NOS2TSHRGABRPGABRDGABRA1
SCHEMBL13949333 0.78 HTT (0.42) HTTPOLBALDH1A1MAPTNOS3
SCHEMBL5374367 0.76 TLR8 (0.40) HTTMAPTMEN1KMT2ACYP3A4
SCHEMBL29639 0.76 NR4A1 (0.50) POLBALDH1A1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165603-A1 Adhesive Composition And Adhesive Film Comprising The Same CHEIL INDUSTRIES, INC. (KR) 2013-06-27 US claimed
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
EP-3623870-B1 IMAGE FORMING APPARATUS AND TONER SET RICOH CO LTD (JP) 2022-05-04 EP disclosed
EP-3418811-B1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER RICOH CO LTD (JP) 2021-07-28 EP disclosed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-10895816-B2 Image forming apparatus and toner set RICOH COMPANY, LTD. (JP) 2021-01-19 US disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
US-20200089140-A1 IMAGE FORMING APPARATUS AND TONER SET RICOH COMPANY, LTD. (JP) 2020-03-19 US disclosed
EP-3623870-A1 IMAGE FORMING APPARATUS AND TONER SET Ricoh Company, Ltd. (JP) 2020-03-18 EP disclosed
US-10429756-B2 Toner, developer, process cartridge, image forming apparatus, image forming method, and method for manufacturing toner RICOH COMPANY, LTD. (JP) 2019-10-01 US disclosed
EP-2898371-B1 TONER, DEVELOPER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2019-09-11 EP disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed