SCHEMBL9682268

SCHEMBL9682268

CCc1cc(Oc2ccc(Cc3ccc(Oc4cc(CC)c(N)c(CC)c4)cc3)cc2)cc(CC)c1N

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.46
SMN1; SMN2 Q16637 5/20 0.42
SRD5A2 P31213 1/20 0.41
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
STS P08842 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
LTA4H P09960 2/20 0.36
ELANE P08246 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619541 0.90 ST14 (0.41) ST14SMN1; SMN2SRD5A2ALDH1A1RAB9A
SCHEMBL9683024 0.86 ST14 (0.43) ST14SMN1; SMN2SRD5A2ALDH1A1RAB9A
SCHEMBL832729 0.84 HTT (0.48) ST14SMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL28069209 0.81 LTA4H (0.52) ALDH1A1POLBHTTMAPTHPGD
SCHEMBL9680517 0.78 ST14 (0.48) ST14SMN1; SMN2SRD5A2ALDH1A1RAB9A
SCHEMBL10508727 0.76 CYP3A4 (0.56) ALDH1A1POLBHTTKMT2A
SCHEMBL29619575 0.76 SMN1; SMN2 (0.35) SMN1; SMN2RAB9ANPC1STSMAPT
SCHEMBL29619560 0.76 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1RAB9ANPC1MEN1
SCHEMBL30026819 0.75 SMN1; SMN2 (0.49) ST14SMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL48459 0.74 HTT (0.50) ALDH1A1POLBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110922594-B High-light-transmittance soluble polyimide and preparation method of film thereof 吉林奥来德光电材料股份有限公司 2022-05-06 CN disclosed
US-5112942-A Copolymers, aromatic diamine with alkyl substituents and phenoxy substituted aromatic diamine, resistance to stess cracking ETHYL CORPORATION (US) 1992-05-12 US disclosed