Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963714 | 0.91 | CYP11B2 (0.34) | CYP11B2PARP1CYP11B1 | |
| SCHEMBL7952345 | 0.91 | CYP11B2 (0.34) | DHODHCYP11B2PARP1CYP11B1PDE4B | |
| SCHEMBL7967763 | 0.88 | HCRTR1 (0.35) | CYP11B2 | |
| SCHEMBL8329854 | 0.88 | DHODH (0.36) | DHODH | |
| SCHEMBL7967472 | 0.86 | CYP11B2 (0.39) | CYP11B2PARP1CYP11B1 | |
| SCHEMBL8328134 | 0.84 | DHODH (0.44) | DHODHNAPRT | |
| SCHEMBL8329857 | 0.84 | DHODH (0.38) | DHODHCYP11B2NAPRTPDE4BPDE4D | |
| SCHEMBL8325506 | 0.82 | DHODH (0.36) | DHODHNAPRT | |
| SCHEMBL8329745 | 0.81 | DHODH (0.38) | DHODHNAPRT | |
| SCHEMBL7960341 | 0.81 | CYP11B2 (0.42) | CYP11B2PARP1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |