Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327806 | 1.00 | POLB (0.44) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL8329755 | 0.91 | KMT2A (0.40) | POLBSNCALMNA | |
| SCHEMBL6944145 | 0.88 | HCAR3 (0.47) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL6944148 | 0.88 | HCAR3 (0.47) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL6378384 | 0.86 | ALDH1A1 (0.48) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL6377823 | 0.86 | ALDH1A1 (0.48) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL8327873 | 0.85 | POLB (0.44) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL8327876 | 0.85 | POLB (0.44) | POLBTSHRCASP6HCAR3SNCA | |
| SCHEMBL8326453 | 0.84 | CDC25B (0.37) | LMNA | |
| SCHEMBL6950389 | 0.84 | POLB (0.49) | POLBTSHRCASP6HCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |