Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328321 | 0.93 | HPGD (0.46) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL22907096 | 0.88 | HPGD (0.41) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL8484859 | 0.84 | HPGD (0.45) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL4102689 | 0.83 | EPHX1 (0.47) | HPGDGPR119MMP13RECQLEPHX1 | |
| SCHEMBL8329690 | 0.82 | KDM4E (0.44) | HPGDGPR119MMP13RECQLEPHX1 | |
| SCHEMBL2720480 | 0.79 | GPR119 (0.50) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL4106700 | 0.78 | EPHX1 (0.50) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL1873727 | 0.78 | EPHX1 (0.50) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL609639 | 0.78 | EPHX1 (0.50) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL4101370 | 0.78 | EPHX1 (0.50) | HPGDGPR119RECQLEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |