Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127777 | 0.84 | GPR119 (0.44) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL14127657 | 0.84 | GPR119 (0.44) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL8328323 | 0.82 | HPGD (0.43) | KDM4EPKMGPR119HPGDMMP13 | |
| SCHEMBL18015126 | 0.80 | HPGD (0.48) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL7385084 | 0.80 | KDM4E (0.46) | KDM4EPKMGPR119HPGDMMP13 | |
| SCHEMBL8634128 | 0.80 | KDM4E (0.46) | KDM4EPKMGPR119HPGDMMP13 | |
| SCHEMBL4596204 | 0.80 | HPGD (0.45) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL6059034 | 0.79 | NR1H2 (0.43) | KDM4EPKMGPR119HPGDMMP13 | |
| SCHEMBL8328321 | 0.78 | HPGD (0.46) | GPR119HPGDRECQLEPHX1DPP4 | |
| SCHEMBL8330217 | 0.78 | HRH3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |