Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349572 | 0.82 | OPRM1 (0.59) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL5175182 | 0.79 | OPRM1 (0.56) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL2303288 | 0.78 | OPRL1 (0.51) | OPRM1OPRL1OPRD1OPRK1ADRA1A | |
| Hydrochloric Acid SCHEMBL7984412 | 0.78 | OPRM1 (0.55) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL7689578 | 0.76 | OPRL1 (0.63) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL28914563 | 0.75 | OPRM1 (0.69) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8986018 | 0.73 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8986110 | 0.73 | SIGMAR1 (0.57) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3091966 | 0.72 | OPRM1 (0.49) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL4204848 | 0.72 | OPRM1 (0.60) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925642-A | ANTITUMOR, ANTIMETASTASIS AGENTS; DRUG RESISTANCE MODULATORS; SYNERGISTIC MIXTURES WITH ANTIBIOTICS AND CYTOSTATIC AGENTS; SIDE EFFECT REDUCTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-20 | — | — | US | disclosed |
| EP-0863899-A1 | PYRIDOPYRIMIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| US-5668131-A | CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-09-16 | — | — | US | disclosed |
| WO-1997019946-A1 | PYRIDOPYRIMIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |