Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.68 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328372 | 1.00 | ADORA3 (0.68) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL13932305 | 0.82 | ADORA3 (1.00) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8330641 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8330644 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8330776 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8330775 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8329083 | 0.80 | ADORA3 (0.64) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8329085 | 0.80 | ADORA3 (0.64) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8323179 | 0.77 | ADORA3 (0.59) | ADORA3TMIGD3KDM4EMAPTALDH1A1 | |
| SCHEMBL8321504 | 0.77 | ADORA3 (0.59) | ADORA3TMIGD3KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |