Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.66 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330776 | 1.00 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8323854 | 0.91 | ADORA3 (0.62) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8323850 | 0.91 | ADORA3 (0.62) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL7869547 | 0.85 | ADORA3 (0.55) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8330644 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8330641 | 0.81 | ADORA3 (0.66) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8328372 | 0.81 | ADORA3 (0.68) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8328375 | 0.81 | ADORA3 (0.68) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL13932305 | 0.80 | ADORA3 (1.00) | ADORA3TMIGD3KDM4EMAPTMEN1 | |
| SCHEMBL8323179 | 0.80 | ADORA3 (0.59) | ADORA3TMIGD3KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |