Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328176 | 0.88 | KMT2A (0.52) | KMT2AMEN1TSHRUSP2RAB9A | |
| SCHEMBL8329478 | 0.86 | MEN1 (0.62) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL8326417 | 0.86 | MEN1 (0.66) | KMT2AMEN1TSHRUSP2L3MBTL1 | |
| SCHEMBL19928034 | 0.69 | MAPT (0.57) | KMT2ATSHRRAB9AL3MBTL1TDP1 | |
| SCHEMBL11796523 | 0.69 | KMT2A (0.59) | KMT2AMEN1RAB9AALDH1A1RECQL | |
| SCHEMBL199583 | 0.69 | KMT2A (0.55) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL17965761 | 0.67 | TDP1 (0.61) | KMT2ATSHRRAB9AL3MBTL1TDP1 | |
| SCHEMBL22327485 | 0.66 | MAPT (0.51) | KMT2ATSHRRAB9AL3MBTL1TDP1 | |
| SCHEMBL23373128 | 0.66 | RAB9A (0.52) | KMT2ATSHRRAB9ACASP3SENP8 | |
| SCHEMBL20154166 | 0.65 | KMT2A (0.54) | KMT2AUSP2RAB9AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |