Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.57 |
| ▸ | HTR3B | O95264 | 3/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.57 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 5/20 | 0.48 |
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8328551 | 0.98 | MEN1 (0.70) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL139363 | 0.85 | KMT2A (1.00) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL24136574 | 0.85 | KMT2A (1.00) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL24662980 | 0.85 | KMT2A (1.00) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL28549744 | 0.83 | KMT2A (0.95) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL9773794 | 0.83 | KMT2A (0.95) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL6967013 | 0.82 | MEN1 (0.76) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7560014 | 0.80 | MEN1 (0.73) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL4862359 | 0.80 | MEN1 (0.73) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL11789365 | 0.80 | CYP2D6 (0.85) | MEN1KMT2AHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |