Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.74 |
| ▸ | DPP4 | P27487 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.74 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.74 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.74 |
| ▸ | GAPDH | P04406 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | STAT6 | P42226 | 1/20 | 0.74 |
| ▸ | PI4KA | P42356 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.74 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.74 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.74 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.74 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581742 | 0.95 | P2RY1 (0.70) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL2270709 | 0.94 | ADORA1 (0.73) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL6828798 | 0.94 | ADORA1 (0.70) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL10786307 | 0.93 | ADORA1 (0.72) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL2534140 | 0.93 | EHMT1 (0.70) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL5509535 | 0.93 | AMD1 (0.66) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL8671033 | 0.92 | EHMT1 (0.74) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL10605538 | 0.92 | ADORA1 (0.66) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL29936475 | 0.92 | EHMT1 (0.74) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL8671037 | 0.92 | EHMT1 (0.74) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713496-A4 | FIBRIN-TARGETED INHIBITORS OF THROMBIN | HARVARD COLLEGE (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0713496-A1 | FIBRIN-TARGETED INHIBITORS OF THROMBIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1996-05-29 | — | — | EP | disclosed |
| WO-1994025491-A1 | FIBRIN-TARGETED INHIBITORS OF THROMBIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1994-11-10 | — | — | WO | disclosed |