Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334628 | 0.93 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6718768 | 0.90 | KMT2A (0.51) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6726360 | 0.88 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6715844 | 0.88 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL8335661 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6726583 | 0.82 | HTT (0.51) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6722817 | 0.80 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6726581 | 0.80 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL8336995 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL6723227 | 0.80 | MEN1 (0.53) | MEN1KMT2AMAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |