Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718768 | 0.92 | KMT2A (0.51) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL8334628 | 0.90 | MEN1 (0.49) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL6726773 | 0.88 | MEN1 (0.62) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL6723227 | 0.87 | MEN1 (0.53) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL8336995 | 0.86 | MEN1 (0.47) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL6726588 | 0.82 | MEN1 (0.46) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL8328544 | 0.82 | MEN1 (0.54) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL6715985 | 0.82 | MEN1 (0.51) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL8334611 | 0.81 | ALDH1A1 (0.62) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL8328720 | 0.81 | ALDH1A1 (0.64) | HTTMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | SLC1A2, SLC1A1, SLC7A11 | HTT 284/4885MEN1 2822/4885KMT2A 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.