Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335661 | 0.93 | MEN1 (0.52) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6718750 | 0.89 | MEN1 (0.57) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL8334628 | 0.87 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6726583 | 0.86 | HTT (0.51) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6723227 | 0.82 | MEN1 (0.53) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6718289 | 0.81 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6719479 | 0.81 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6715985 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL8328544 | 0.80 | MEN1 (0.54) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6718768 | 0.78 | KMT2A (0.51) | MEN1KMT2AMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |