SCHEMBL8328571

SCHEMBL8328571

CON=CC(=O)Nc1ccccc1COc1ccccc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.45
RECQL P46063 1/20 0.45
MEN1 O00255 2/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 2/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
NOTUM Q6P988 1/20 0.40
MMP1 P03956 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5713107 0.87 RECQL (0.44) KMT2ARECQLMEN1LMNANPSR1
SCHEMBL7639450 0.87 RECQL (0.44) KMT2ARECQLMEN1LMNANPSR1
SCHEMBL8174651 0.81 KMT2A (0.51) KMT2ARECQLMEN1LMNANPSR1
SCHEMBL26639941 0.80 MMP1 (0.56) LMNAHPGDMAPTALDH1A1POLB
SCHEMBL25357010 0.80 MMP1 (0.56) LMNAHPGDMAPTALDH1A1POLB
SCHEMBL7511864 0.80 HPGD (0.41) KMT2AMEN1LMNAHPGDL3MBTL1
SCHEMBL8442960 0.79 HPGD (0.47) LMNAHPGDMAPTALDH1A1POLB
SCHEMBL9422372 0.79 RECQL (0.47) KMT2ARECQLNPSR1MAPTTDP1
SCHEMBL8167451 0.77 ALDH1A1 (0.51) KMT2ARECQLMEN1LMNANPSR1
SCHEMBL8647160 0.76 KMT2A (0.43) KMT2AMEN1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0772587-B1 N-ALKOXY-AMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1999-10-06 EP disclosed
EP-0772587-A1 N-ALKOXY-AMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1997-05-14 EP disclosed
WO-1996004239-A1 N-ALKOXY-AMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-02-15 WO disclosed