Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638904 | 0.94 | ACAT1 (0.62) | ACAT1SOAT1 | |
| SCHEMBL8323473 | 0.90 | ACAT1 (0.54) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8330240 | 0.90 | ACAT1 (0.53) | ACAT1SOAT1 | |
| SCHEMBL8328479 | 0.89 | ACAT1 (0.69) | ACAT1SOAT1 | |
| SCHEMBL8326346 | 0.89 | ACAT1 (0.69) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8329227 | 0.89 | ACAT1 (0.57) | ACAT1SOAT1KDM4ENSD2ALDH1A1 | |
| SCHEMBL8324948 | 0.88 | ACAT1 (0.52) | ACAT1SOAT1 | |
| SCHEMBL8326851 | 0.85 | ACAT1 (0.62) | ACAT1SOAT1 | |
| SCHEMBL8325491 | 0.85 | ACAT1 (0.64) | ACAT1SOAT1 | |
| SCHEMBL8322732 | 0.84 | ACAT1 (0.55) | ACAT1SOAT1KDM4ENSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |