Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329528 | 0.82 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8329392 | 0.81 | KDM4E (0.63) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8085582 | 0.80 | DRD2 (0.74) | MAPTSMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL29608207 | 0.80 | DRD2 (0.74) | MAPTSMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL8085594 | 0.79 | SMN1; SMN2 (0.64) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL7318618 | 0.78 | SMN1; SMN2 (0.65) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL8085463 | 0.78 | DRD2 (0.67) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| Hydrochloric Acid SCHEMBL8091842 | 0.77 | DRD2 (0.66) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL3426740 | 0.76 | NPC1 (1.00) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL8078654 | 0.75 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935599-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998018797-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1998-05-07 | — | — | WO | disclosed |