Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | GAA | P10253 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | GLA | P06280 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329528 | 0.85 | NPC1 (0.65) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8328706 | 0.81 | MAPT (0.60) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8085579 | 0.80 | ALDH1A1 (0.66) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL8091851 | 0.80 | DRD2 (0.78) | ALDH1A1SMN1; SMN2MAPTDRD2DRD3 | |
| SCHEMBL8086614 | 0.79 | ALDH1A1 (0.67) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL10753716 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL8078634 | 0.78 | DRD2 (0.77) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL8091832 | 0.77 | DRD2 (0.70) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL8086607 | 0.77 | ALDH1A1 (0.67) | KDM4EALDH1A1GAARAB9AGLA | |
| SCHEMBL7318575 | 0.74 | HRH3 (0.72) | KDM4EALDH1A1GAARAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935599-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998018797-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1998-05-07 | — | — | WO | disclosed |