SCHEMBL8328784

SCHEMBL8328784

CS(=O)(=O)c1nc2c(Cl)cc(Cl)c(N)c2s1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 10/20 0.41
SMN1; SMN2 Q16637 1/20 0.34
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA9 Q16790 3/20 0.33
NQO2 P16083 1/20 0.33
ALDH1A1 P00352 1/20 0.33
IKBKB O14920 1/20 0.32
CHUK O15111 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8334293 0.76 MAPK1 (0.34) GLP1RTDP1
SCHEMBL8331881 0.75 TLR8 (0.39) SMN1; SMN2NQO2ALDH1A1POLBL3MBTL1
SCHEMBL8688647 0.74 SMN1; SMN2 (0.41) SMN1; SMN2NQO2ALDH1A1POLBL3MBTL1
SCHEMBL8331007 0.71 KDR (0.39) GLP1RSMN1; SMN2NQO2ALDH1A1POLB
SCHEMBL16835616 0.65 IKBKB (0.33) IKBKBCHUK
SCHEMBL10967898 0.62 ALDH1A1 (0.58) GLP1RSMN1; SMN2ALDH1A1
SCHEMBL1449764 0.62 CA1 (0.64) GLP1RCA1CA2CA9ALDH1A1
SCHEMBL8334566 0.61 TLR8 (0.36) SMN1; SMN2CA1CA2CA9ALDH1A1
SCHEMBL16793818 0.61 AXL (0.33) IKBKBCHUKTDP1
SCHEMBL16835641 0.61 GAA (0.34) CA1CA2CA9IKBKBCHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5888940-A DESICCATING PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-30 US disclosed
EP-0862569-A1 SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1998-09-09 EP disclosed
WO-1997008171-A1 SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed