Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331898 | 0.86 | KDR (0.36) | KDRSMN1; SMN2NPSR1KEAP1ALDH1A1 | |
| SCHEMBL8331881 | 0.77 | TLR8 (0.39) | SMN1; SMN2ALDH1A1NQO2KMT2APKM | |
| SCHEMBL8688647 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NQO2KMT2AMEN1 | |
| SCHEMBL8691426 | 0.77 | SMN1; SMN2 (0.47) | KDRSMN1; SMN2NPSR1KEAP1ALDH1A1 | |
| SCHEMBL8331581 | 0.74 | ALDH1A1 (0.39) | KDRSMN1; SMN2NPSR1KEAP1ALDH1A1 | |
| SCHEMBL8328784 | 0.71 | GLP1R (0.41) | SMN1; SMN2ALDH1A1NQO2POLBGLP1R | |
| SCHEMBL8331829 | 0.69 | ALDH1A1 (0.56) | KDRSMN1; SMN2NPSR1KEAP1ALDH1A1 | |
| SCHEMBL8333397 | 0.67 | KDR (0.32) | KDRSMN1; SMN2NPSR1 | |
| SCHEMBL8333567 | 0.67 | SMN1; SMN2 (0.45) | KDRSMN1; SMN2NPSR1KEAP1ALDH1A1 | |
| SCHEMBL8334566 | 0.63 | TLR8 (0.36) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888940-A | DESICCATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0862569-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997008171-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |