Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530966 | 0.82 | TDP1 (0.35) | TDP1TSHR | |
| SCHEMBL2225856 | 0.79 | — | — | |
| SCHEMBL27864231 | 0.75 | TSHR (0.50) | TDP1TSHRALDH1A1 | |
| SCHEMBL2455808 | 0.73 | TDP1 (0.40) | TDP1TSHRALDH1A1 | |
| SCHEMBL27528744 | 0.71 | — | — | |
| SCHEMBL27432162 | 0.71 | MEN1 (0.34) | TSHR | |
| SCHEMBL992741 | 0.71 | TDP1 (0.33) | TDP1TSHR | |
| SCHEMBL9934057 | 0.71 | TDP1 (0.33) | TDP1TSHR | |
| SCHEMBL1328556 | 0.69 | TDP1 (0.31) | TDP1TSHR | |
| SCHEMBL27280583 | 0.68 | TSHR (0.48) | TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864032-A | Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides | AMERSHAM INTERNATIONAL PLC (GB) | 1999-01-26 | — | — | US | disclosed |
| US-5567811-A | Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides | AMERSHAM INTERNATIONAL PLC (GB) | 1996-10-22 | — | — | US | disclosed |
| EP-0527184-B1 | PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES | AMERSHAM INT PLC (GB) | 1995-08-02 | — | — | EP | disclosed |
| EP-0527184-A1 | PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES. | AMERSHAM INT PLC (GB) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017169-A1 | PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES | AMERSHAM INTERNATIONAL PLC (GB) | 1991-11-14 | — | — | WO | disclosed |