Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 5/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328912 | 1.00 | ADK (0.61) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8975011 | 0.89 | ADORA3 (0.66) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8975466 | 0.89 | ADK (0.61) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8975239 | 0.85 | ADK (0.71) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8332277 | 0.85 | ADK (0.59) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8332286 | 0.85 | ADK (0.59) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8327965 | 0.79 | ADK (0.69) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8975362 | 0.78 | ADORA3 (0.66) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8331212 | 0.77 | ADK (0.71) | ADKADORA3SLC29A1TP53TDP1 | |
| SCHEMBL8975520 | 0.76 | ADK (0.75) | ADKSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |