Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493853 | 0.77 | KDM4E (0.60) | HTTTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15440468 | 0.77 | LMNA (0.49) | HTTTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31478177 | 0.76 | MEN1 (0.41) | TSHRSMN1; SMN2MEN1KMT2ACRHBP | |
| SCHEMBL31478121 | 0.76 | MEN1 (0.41) | TSHRSMN1; SMN2MEN1KMT2ACRHBP | |
| SCHEMBL6181078 | 0.75 | RXFP1 (0.38) | SMN1; SMN2ELANEPOLBLMNACYP2C9 | |
| SCHEMBL4050633 | 0.75 | CNR2 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26745357 | 0.74 | CYP1A2 (0.54) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL16183923 | 0.74 | CYP1A2 (0.54) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28465214 | 0.72 | TSHR (0.51) | HTTCASP3SENP8SENP7SENP6 | |
| SCHEMBL2703465 | 0.72 | ALDH1A1 (0.54) | HTTGAAKMT2AELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |