Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325128 | 0.93 | DRD4 (0.41) | DRD4TSHRDPP4KCNH2CNR2 | |
| SCHEMBL8324228 | 0.84 | DRD4 (0.41) | DRD4DPP4KCNH2CNR2HSD17B10 | |
| SCHEMBL8330206 | 0.80 | DRD4 (0.39) | DRD4TSHRCNR2HSD17B10KDM4E | |
| SCHEMBL8329132 | 0.80 | DRD4 (0.47) | DRD4KCNH2HSD17B10GAA | |
| SCHEMBL8325130 | 0.77 | DRD4 (0.47) | DRD4KCNH2 | |
| SCHEMBL8326763 | 0.75 | DRD4 (0.41) | DRD4CNR2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8330688 | 0.74 | DRD4 (0.47) | DRD4KCNH2 | |
| SCHEMBL8327397 | 0.71 | GRIN2B (0.38) | DRD4KCNH2MOGAT2MGAT2 | |
| SCHEMBL8329835 | 0.71 | DRD4 (0.35) | DRD4TSHRCNR2ALDH1A1HTT | |
| SCHEMBL8329087 | 0.71 | DRD4 (0.47) | DRD4TSHRKCNH2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |