Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324228 | 0.84 | DRD4 (0.41) | GRIN2BDRD4MOGAT2MGAT2KCNH2 | |
| SCHEMBL8326763 | 0.83 | DRD4 (0.41) | GRIN2BDRD4MOGAT2MGAT2DRD3 | |
| SCHEMBL8327400 | 0.82 | DRD4 (0.41) | GRIN2BDRD4MOGAT2MGAT2KCNH2 | |
| SCHEMBL8329835 | 0.78 | DRD4 (0.35) | GRIN2BDRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8330206 | 0.76 | DRD4 (0.39) | GRIN2BDRD4MOGAT2MGAT2DRD3 | |
| SCHEMBL8327693 | 0.74 | DRD4 (0.41) | DRD4MOGAT2KCNH2MLNRDRD3 | |
| SCHEMBL8329877 | 0.74 | DRD4 (0.43) | DRD4KCNH2MEN1LMNACYP1A2 | |
| SCHEMBL8329875 | 0.74 | DRD4 (0.43) | DRD4KCNH2MEN1LMNACYP1A2 | |
| SCHEMBL8326476 | 0.73 | DRD4 (0.40) | GRIN2BDRD4KCNH2MLNRMEN1 | |
| SCHEMBL8325128 | 0.73 | DRD4 (0.41) | DRD4MOGAT2MGAT2KCNH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |